How does Semaglutide Work
Semaglutide is most known to treat type 2 diabetes. It is most commonly prescribed as an injection (Wegovy). In clinical studies, it was found to help in weight loss in patients who do not have diabetes.
Semaglutide is classified as a GLP-1 receptor agonist. GLP-1 is a hormone that is naturally produced in our bodies by the small intestines. It helps us to feel satisfied after a meal. GLP-1 also helps decrease blood glucose levels and stimulate the production of insulin. A diabetic doesn’t produce enough GLP-1 to control glucose levels, so Semaglutide helps with this production.
Semaglutide is a synthetic version of GLP-1. This modification helps it to last longer and not be broken down by enzymes in the body aiding in weight loss. This is why injections are weekly. Gastric emptying is also delayed with the result in fewer intake of calories.
Semaglutide has been approved for weight loss in patients without diabetes and can be prescribed by a provider if they feel it will help in weight loss. A healthy diet and exercise program are also recommended.
Patients taking Semaglutide should lose around 15% of their starting weight. Keep in mind you will need to be on a treatment plan for at least a few months for the full effect. For example, if you weigh 200lbs, you could lose 30lbs. During this time, the dose will be increased incrementally. If for some reason you are not losing weight, Semaglutide may not be the right choice for you and other options will be discussed.
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The injections aid in weight loss by increasing the production of insulin that helps to regulate blood sugar and makes you feel fuller so you consume fewer calories. You can use this even if you are not a diabetic because it will not lower your blood sugar levels.